Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 4/20 | 0.53 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.53 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.53 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18520986 | 0.83 | YTHDC1 (0.63) | CDK1CCNB2CCNB1CCNB3TMIGD3 | |
| SCHEMBL28252137 | 0.81 | CDK1 (0.53) | CDK1CCNB2CCNB1CCNB3TMIGD3 | |
| SCHEMBL22326727 | 0.81 | ADORA2A (0.69) | CDK1CCNB2CCNB1CCNB3TMIGD3 | |
| SCHEMBL21539428 | 0.81 | CDK1 (0.53) | CDK1CCNB2CCNB1CCNB3TMIGD3 | |
| SCHEMBL18521194 | 0.79 | CCNB2 (0.82) | CDK1CCNB2CCNB1CCNB3TMIGD3 | |
| SCHEMBL20041716 | 0.78 | YTHDC1 (0.66) | ADORA2AADORA1ADORA2BPDE4APDE4B | |
| SCHEMBL21539482 | 0.77 | CCNB2 (0.66) | CDK1CCNB2CCNB1CCNB3TMIGD3 | |
| Dimethylamine SCHEMBL4143569 | 0.76 | SRC (0.49) | CDK1CCNB2CCNB1CCNB3TMIGD3 | |
| SCHEMBL28004446 | 0.72 | YTHDC1 (0.41) | CDK1CCNB2CCNB1CCNB3ADORA2A | |
| SCHEMBL21029515 | 0.70 | NPC1 (0.64) | CDK1CCNB2CCNB1CCNB3SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108703970-A | Compound for activating AMPK and application thereof | 华安医学股份有限公司 | 2018-10-26 | — | — | CN | disclosed |