SCHEMBL28253003

SCHEMBL28253003

O=Nc1ccc(N=O)c(Cl)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
HTR3E A5X5Y0 2/20 0.34
HTR3B O95264 2/20 0.34
HTR3A P46098 2/20 0.34
HTR3D Q70Z44 2/20 0.34
HTR3C Q8WXA8 2/20 0.34
ALDH1A1 P00352 4/20 0.34
HSD17B10 Q99714 4/20 0.34
TSHR P16473 3/20 0.34
TP53 P04637 2/20 0.34
HIF1A Q16665 2/20 0.34
KMT2A Q03164 2/20 0.34
CYP3A4 P08684 2/20 0.34
LMNA P02545 2/20 0.34
MEN1 O00255 1/20 0.34
GMNN O75496 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12216540 0.81 TDP1 (0.43) MAPK1TDP1HTR3EHTR3BHTR3A
SCHEMBL12116179 0.80 MAPK1 (0.58) MAPK1TDP1HTR3EHTR3BHTR3A
SCHEMBL30396176 0.80 MAPK1 (0.58) MAPK1TDP1HTR3EHTR3BHTR3A
SCHEMBL28052344 0.80 TDP1 (0.40) MAPK1TDP1ALDH1A1HSD17B10CYP3A4
SCHEMBL9290659 0.78 TP53 (0.48) MAPK1TDP1ALDH1A1HSD17B10TSHR
SCHEMBL31218219 0.78 TP53 (0.48) MAPK1TDP1ALDH1A1HSD17B10TSHR
SCHEMBL14074204 0.78 AHR (0.48) MAPK1TDP1ALDH1A1TSHRKMT2A
SCHEMBL12028610 0.74 HPGD (0.36) ALDH1A1KMT2ACYP3A4LMNAMEN1
SCHEMBL13131511 0.74 IDO1 (0.50) MAPK1TDP1ALDH1A1TSHRKMT2A
SCHEMBL7878843 0.74 CYP3A4 (0.52) TDP1ALDH1A1HSD17B10TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104781329-B Improved cementing compositions 汉高知识产权控股有限责任公司 2018-11-09 CN disclosed