Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6598241 | 0.87 | — | — | |
| Bromide SCHEMBL118850 | 0.82 | — | — | |
| Bromide SCHEMBL8629282 | 0.82 | — | — | |
| Bromide SCHEMBL449 | 0.82 | — | — | |
| Bromide SCHEMBL7076360 | 0.82 | — | — | |
| Bromide SCHEMBL21364 | 0.82 | — | — | |
| Bromide SCHEMBL3725335 | 0.82 | — | — | |
| Bromide SCHEMBL8771974 | 0.82 | — | — | |
| Bromide SCHEMBL8689591 | 0.67 | — | — | |
| Bromide SCHEMBL7934371 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727284-B | Preparation method of gefitinib | 鲁南制药集团股份有限公司 | 2020-10-27 | — | — | CN | claimed |
| CN-108727284-A | A kind of preparation method of Gefitinib | 鲁南制药集团股份有限公司 | 2018-11-02 | — | — | CN | claimed |
| CN-108727284-B | Preparation method of gefitinib | 鲁南制药集团股份有限公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-108727284-A | A kind of preparation method of Gefitinib | 鲁南制药集团股份有限公司 | 2018-11-02 | — | — | CN | disclosed |