Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28253261 | 0.87 | — | — | |
| SCHEMBL28227795 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL4235228 | 0.75 | — | — | |
| Bromide SCHEMBL8723977 | 0.75 | — | — | |
| Bromide SCHEMBL8723975 | 0.75 | — | — | |
| Bromide SCHEMBL21364 | 0.71 | — | — | |
| Bromide SCHEMBL3725335 | 0.71 | — | — | |
| SCHEMBL80 | 0.71 | — | — | |
| SCHEMBL1978498 | 0.71 | — | — | |
| Bromide SCHEMBL7076360 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237889-B1 | ANTIBIOTIC SULTAM AND SULTONE DERIVED OXAZOLIDINONES | UPJOHN CO (US) | 2004-09-01 | — | — | EP | disclosed |
| CN-1146564-C | Antibacterial sultam and sultone derived oxazolidinones | �������Ŷ���Լ��������˾ | 2004-04-21 | — | — | CN | disclosed |
| CN-1378546-A | Antibiotic sultam and sultone drived oxazolidiones | UPJOHN CO (US) | 2002-11-06 | — | — | CN | disclosed |
| EP-1237889-A1 | ANTIBIOTIC SULTAM AND SULTONE DERIVED OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2002-09-11 | — | — | EP | disclosed |
| US-6420360-B1 | ANTIBIOTIC AGENTS. | PHARMACIA & UPJOHN COMPANY | 2002-07-16 | — | — | US | disclosed |
| US-20020055505-A1 | SULTAM AND SULTONE DERIVED OXAZOLIDINONES | ANDERSON DAVID JOHN (US) | 2002-05-09 | — | — | US | disclosed |
| US-6348459-B1 | DRUGS AND ANTIBIOTIC AGENTS. | PHARMACIA AND UPJOHN COMPANY | 2002-02-19 | — | — | US | disclosed |
| WO-2001032657-A1 | ANTIBIOTIC SULTAM AND SULTONE DERIVED OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2001-05-10 | — | — | WO | disclosed |