Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 10/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28181158 | 0.81 | GRIK1 (0.34) | METAP1NOS1 | |
| SCHEMBL28077575 | 0.80 | RNPEP (0.37) | MARS1METAP2METAP1NOS2RNPEP | |
| SCHEMBL22690120 | 0.79 | DPP7 (0.40) | METAP1NOS2NOS3NOS1CYP2C19 | |
| SCHEMBL1732378 | 0.78 | ALOX15 (0.32) | — | |
| SCHEMBL16412363 | 0.75 | GSR (0.47) | NOS2RNPEPNOS3NOS1 | |
| Urea SCHEMBL17442880 | 0.75 | GRM8 (0.46) | ANPEPENPEPCYP2C19 | |
| SCHEMBL20945360 | 0.75 | GSR (0.47) | NOS2RNPEPNOS3NOS1 | |
| SCHEMBL20996747 | 0.75 | RNPEP (0.42) | MARS1METAP2METAP1RNPEPANPEP | |
| SCHEMBL6045793 | 0.75 | RNPEP (0.42) | MARS1METAP2METAP1RNPEPANPEP | |
| SCHEMBL5617582 | 0.75 | RNPEP (0.42) | MARS1METAP2METAP1RNPEPANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104411332-B | Human antibody in conjunction with VEGFR2 | 索伦托治疗有限公司 | 2018-11-23 | — | — | CN | disclosed |