Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | CETP | P11597 | 7/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1555946 | 0.86 | CYP4F2 (0.52) | CYP4F2CYP4A11CETPCTSKP4HB | |
| SCHEMBL9720226 | 0.85 | CYP4F2 (0.64) | CYP4F2CYP4A11CETPCTSKCYP2C19 | |
| SCHEMBL22071050 | 0.85 | CYP4F2 (0.58) | CYP4F2CYP4A11CTSKP4HBDGAT1 | |
| SCHEMBL19176811 | 0.84 | CYP4F2 (0.42) | CYP4F2CYP4A11CTSKP4HB | |
| SCHEMBL22071018 | 0.83 | CYP4F2 (0.66) | CYP4F2CYP4A11CTSKP4HBDGAT1 | |
| SCHEMBL5052685 | 0.82 | CYP4F2 (0.50) | CYP4F2CYP4A11CETPCYP2C19MEN1 | |
| SCHEMBL22070514 | 0.82 | CYP4F2 (0.44) | CYP4F2CYP4A11CTSKCYP2C19P4HB | |
| SCHEMBL23384 | 0.81 | CYP4F2 (0.49) | CYP4F2CYP4A11CETPCYP2C19MEN1 | |
| SCHEMBL28199817 | 0.81 | CYP4F2 (0.67) | CYP4F2CYP4A11CETPCYP2C19MEN1 | |
| SCHEMBL798441 | 0.80 | CYP4F2 (0.60) | CYP4F2CYP4A11CTSKP4HBDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189508-B | Naphthenic base nitrile Pyrazolopyridine ketone as JANUS kinase inhibitor | 默沙东公司 | 2018-11-23 | — | — | CN | disclosed |