Methylene Chloride

Methylene Chloride

SCHEMBL28255147

CCN1CCOCC1.ClCCl

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.41
USP2 O75604 1/20 0.41
HRH3 Q9Y5N1 3/20 0.40
KDM4E B2RXH2 3/20 0.39
ALDH1A1 P00352 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KEAP1 Q14145 1/20 0.39
HSD17B10 Q99714 2/20 0.38
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
CYP2A13 Q16696 1/20 0.36
CYP1A2 P05177 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM1 P11229 1/20 0.36
HTR2A P28223 1/20 0.36
MAPK1 P28482 1/20 0.36
SCN1A P35498 1/20 0.36
HTR2B P41595 1/20 0.36
KCNH2 Q12809 1/20 0.36
SCN2A Q99250 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8135220 0.92
SCHEMBL28231022 0.92 USP2 (0.46) GAAUSP2HRH3KDM4EALDH1A1
Fluoride SCHEMBL11426086 0.92 USP2 (0.46) GAAUSP2HRH3KDM4EALDH1A1
SCHEMBL3167 0.92
SCHEMBL474212 0.92
SCHEMBL15265769 0.92 USP2 (0.46) GAAUSP2HRH3KDM4EALDH1A1
Fluoride SCHEMBL7750159 0.92
SCHEMBL23481366 0.89 ALDH1A1 (0.48) GAAUSP2HRH3KDM4EALDH1A1
SCHEMBL184123 0.89
Iodide SCHEMBL10383439 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108864192-A Function modified oligonucleotides and its subunit 萨勒普塔医疗公司 2018-11-23 CN disclosed