Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ELANE | P08246 | 3/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | APEX1 | P27695 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792240 | 0.85 | MEN1 (0.74) | ALDH1A1MAPTCYP3A4MEN1KMT2A | |
| SCHEMBL16226134 | 0.84 | LCK (0.59) | ALDH1A1MAPTCYP3A4MEN1KMT2A | |
| SCHEMBL28255177 | 0.83 | PIM1 (0.55) | ALDH1A1MAPTCYP3A4MEN1KMT2A | |
| Questin SCHEMBL29359576 | 0.82 | ELANE (0.73) | ALDH1A1MAPTCYP3A4MEN1KMT2A | |
| 1-O-Methylemodin SCHEMBL16225819 | 0.82 | ELANE (0.73) | ALDH1A1MAPTCYP3A4MEN1KMT2A | |
| SCHEMBL23199006 | 0.82 | ALDH1A1 (0.73) | ALDH1A1MAPTCYP3A4MEN1KMT2A | |
| Questin SCHEMBL15676283 | 0.82 | ELANE (0.73) | ALDH1A1MAPTCYP3A4MEN1KMT2A | |
| Nobilone SCHEMBL30502482 | 0.81 | ESR1 (0.58) | ALDH1A1MAPTCYP3A4MEN1KMT2A | |
| SCHEMBL16226349 | 0.79 | ELANE (0.60) | ALDH1A1MAPTCYP3A4MEN1KMT2A | |
| SCHEMBL16226585 | 0.79 | BCL2 (0.62) | ALDH1A1MAPTCYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108743573-B | Application of fluorenone compound in dendrobium nobile in preparation of medicament for preventing and treating diabetes and preparation method thereof | 云南省农业科学院质量标准与检测技术研究所 | 2020-07-24 | — | — | CN | disclosed |
| CN-108743573-A | Fluorenes ketone compounds are preparing the application and preparation method thereof in preventing diabetes medicament in the stem of noble dendrobium | 云南省农业科学院质量标准与检测技术研究所 | 2018-11-06 | — | — | CN | disclosed |