SCHEMBL28255232

SCHEMBL28255232

NC(=O)NC1CCNc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BDKRB1 P46663 1/20 0.43
HDAC1 Q13547 1/20 0.42
OPRK1 P41145 13/20 0.40
OPRD1 P41143 1/20 0.39
F12 P00748 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1872257 0.86 BDKRB1 (0.46) BDKRB1HDAC1OPRK1OPRD1
SCHEMBL6245119 0.84 BDKRB1 (0.45) BDKRB1HDAC1OPRK1OPRD1
Hydrochloric Acid SCHEMBL1873147 0.84 BDKRB1 (0.45) BDKRB1HDAC1OPRK1OPRD1
SCHEMBL23469157 0.82 HTT (0.56) HDAC1
SCHEMBL22732073 0.82 TEAD1 (0.43) BDKRB1HDAC1OPRK1OPRD1
SCHEMBL6579209 0.82 BDKRB1 (0.44) BDKRB1HDAC1OPRK1OPRD1F12
SCHEMBL7683535 0.81 BDKRB1 (0.50) BDKRB1OPRK1OPRD1F12
SCHEMBL1932403 0.77 EPHX2 (0.53) BDKRB1OPRK1
SCHEMBL30899467 0.76 F12 (0.48) F12
SCHEMBL1906311 0.76 F12 (0.48) F12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108929340-A Proline boric acid compound and its preparation method and application 北京大学 2018-12-04 CN disclosed