Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | F12 | P00748 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1932403 | 0.86 | EPHX2 (0.53) | BDKRB1OPRK1KMT2A | |
| SCHEMBL6245119 | 0.85 | BDKRB1 (0.45) | BDKRB1OPRK1HDAC1OPRD1 | |
| SCHEMBL1872257 | 0.83 | BDKRB1 (0.46) | BDKRB1OPRK1HTR2CHDAC1OPRD1 | |
| Hydrochloric Acid SCHEMBL1873147 | 0.82 | BDKRB1 (0.45) | BDKRB1OPRK1HTR2CHDAC1OPRD1 | |
| SCHEMBL28255232 | 0.82 | BDKRB1 (0.43) | BDKRB1OPRK1F12HDAC1OPRD1 | |
| SCHEMBL6281097 | 0.81 | NAAA (0.52) | OPRK1OPRD1NAAA | |
| SCHEMBL7683535 | 0.81 | BDKRB1 (0.50) | BDKRB1OPRK1F12OPRD1MEN1 | |
| SCHEMBL23469157 | 0.79 | HTT (0.56) | HDAC1MEN1KMT2A | |
| SCHEMBL22732073 | 0.79 | TEAD1 (0.43) | BDKRB1OPRK1HDAC1OPRD1KMT2A | |
| SCHEMBL12535576 | 0.76 | PDPK1 (0.50) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399190-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING LOW-SOLUBILITY AND/OR ACID-SENSITIVE DRUGS AND NEUTRALIZED ACIDIC POLYMERS | Pfizer Products Inc. (US) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003000292-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING LOW-SOLUBILITY AND/OR ACID-SENSITIVE DRUGS AND NEUTRALIZED ACIDIC POLYMERS | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | disclosed |