Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.63 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.60 |
| ▸ | LTA4H | P09960 | 5/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28255251 | 1.00 | ACE (0.63) | ACEACE2LTA4H | |
| SCHEMBL30974292 | 0.98 | ACE (0.61) | ACEACE2 | |
| SCHEMBL30123533 | 0.95 | SLC6A2 (0.62) | ACE | |
| SCHEMBL31039947 | 0.95 | SLC6A2 (0.62) | ACE | |
| SCHEMBL29666711 | 0.94 | ACE (0.59) | ACEACE2 | |
| SCHEMBL29666878 | 0.94 | ACE (0.58) | ACEACE2LTA4H | |
| SCHEMBL30608509 | 0.94 | ACE (0.61) | ACEACE2LTA4H | |
| SCHEMBL30785955 | 0.93 | ACE (0.56) | ACEACE2LTA4H | |
| SCHEMBL8250626 | 0.92 | OPRM1 (0.60) | ACE | |
| SCHEMBL31499407 | 0.91 | SLC6A2 (0.56) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929340-A | Proline boric acid compound and its preparation method and application | 北京大学 | 2018-12-04 | — | — | CN | claimed |
| CN-108929340-A | Proline boric acid compound and its preparation method and application | 北京大学 | 2018-12-04 | — | — | CN | disclosed |