SCHEMBL28255491

SCHEMBL28255491

COc1cc(CN)c(N2C(=O)CSC2c2ccc(F)cc2)cc1OC

nearest known ligand 0.72

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 19/20 0.72
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
GFER P55789 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19306343 0.84 HTR7 (1.00) HTR7
SCHEMBL28866261 0.84 HTR7 (0.53) HTR7
SCHEMBL19306248 0.82 HTR7 (1.00) HTR7MEN1KMT2AGFER
SCHEMBL19305982 0.81 HTR7 (1.00) HTR7MEN1KMT2AGFER
SCHEMBL19306337 0.80 HTR7 (1.00) HTR7MEN1KMT2AGFER
SCHEMBL30876421 0.80 HTR7 (1.00) HTR7MEN1KMT2AGFER
SCHEMBL28255516 0.80 HTR7 (0.73) HTR7MEN1KMT2A
SCHEMBL19306061 0.79 HTR7 (1.00) HTR7MEN1KMT2AGFER
SCHEMBL19306460 0.78 HTR7 (1.00) HTR7MEN1KMT2AGFER
SCHEMBL19306231 0.78 HTR7 (1.00) HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108883099-A THIAZOLIDINONE COMPOUNDS AND USE THEREOF 石全 2018-11-23 CN disclosed