Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | MAPT | P10636 | 10/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28254732 | 0.84 | GFER (0.46) | GFERALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL28255840 | 0.83 | GFER (0.45) | GFERALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL28254690 | 0.82 | GFER (0.47) | GFERALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL5180830 | 0.81 | MAPT (0.60) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6847021 | 0.81 | MAPT (0.60) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL13779247 | 0.79 | NPC1 (0.72) | GFERALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL28253899 | 0.78 | MEN1 (0.42) | GFERALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL28255839 | 0.77 | NQO2 (0.43) | GFERALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL28254744 | 0.77 | GAA (0.49) | GFERALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL21294997 | 0.74 | CHRM5 (0.53) | GFERALDH1A1MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863914-A | The hydrazide derivatives and application thereof that pyridine replaces | 广东东阳光药业有限公司 | 2018-11-23 | — | — | CN | disclosed |