Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.72 |
| ▸ | RAB9A | P51151 | 7/20 | 0.72 |
| ▸ | GAA | P10253 | 7/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | GFER | P55789 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9442365 | 0.82 | RAB9A (0.74) | NPC1RAB9AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL9442364 | 0.82 | RAB9A (0.74) | NPC1RAB9AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL11486327 | 0.82 | ALDH1A1 (0.74) | NPC1RAB9AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL11226669 | 0.82 | ALDH1A1 (0.74) | NPC1RAB9AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL9173819 | 0.79 | ABL1 (0.47) | NPC1RAB9AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL28255841 | 0.79 | GFER (0.65) | NPC1RAB9AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL2790144 | 0.77 | RAB9A (0.52) | NPC1RAB9AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL19034090 | 0.75 | NOX1 (0.67) | NPC1RAB9AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL11674750 | 0.75 | NOX1 (0.67) | NPC1RAB9AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL11674747 | 0.75 | NOX1 (0.67) | NPC1RAB9AGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | PRKCH, AIP, PRKCE | NPC1 1716/4885RAB9A 959/4885GAA 941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.