Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | USP2 | O75604 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | CASP1 | P29466 | 2/20 | 0.69 |
| ▸ | CASP7 | P55210 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246464 | 0.82 | KDM4E (1.00) | MEN1KMT2AKDM4EUSP2MAPK1 | |
| SCHEMBL20923496 | 0.78 | KMT2A (0.68) | MEN1KMT2AKDM4EUSP2MAPK1 | |
| SCHEMBL31723118 | 0.78 | KMT2A (0.68) | MEN1KMT2AKDM4EUSP2MAPK1 | |
| SCHEMBL28455071 | 0.77 | KMT2A (0.62) | MEN1KMT2AKDM4EUSP2MAPK1 | |
| SCHEMBL1534666 | 0.76 | KMT2A (0.65) | MEN1KMT2AKDM4EUSP2MAPK1 | |
| SCHEMBL29501080 | 0.76 | KMT2A (0.65) | MEN1KMT2AKDM4EUSP2MAPK1 | |
| SCHEMBL11634332 | 0.75 | KDM4E (0.64) | MEN1KMT2AKDM4EUSP2MAPK1 | |
| SCHEMBL11637200 | 0.74 | KDM4E (0.62) | MEN1KMT2AKDM4EUSP2MAPK1 | |
| SCHEMBL9387204 | 0.73 | KDM4E (0.57) | MEN1KMT2AKDM4EUSP2MAPK1 | |
| SCHEMBL7369040 | 0.73 | NTRK1 (0.53) | MEN1KMT2AKDM4EUSP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632194-B | The method that Benzofurantone compound is prepared as CO source of release using iron pentacarbonyl | 陕西师范大学 | 2018-12-07 | — | — | CN | disclosed |