SCHEMBL28256405

SCHEMBL28256405

CCN(CC)c1ccc(C(=O)Nc2ccc3c(c2)CCC3)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 11/20 0.67
NPC1 O15118 10/20 0.67
SMN1; SMN2 Q16637 6/20 0.67
NFKB1 P19838 4/20 0.67
NFKB2 Q00653 4/20 0.67
RELA Q04206 4/20 0.67
MAPT P10636 4/20 0.67
ALDH1A1 P00352 3/20 0.67
TP53 P04637 2/20 0.64
HTT P42858 3/20 0.63
GAA P10253 1/20 0.63
KMT2A Q03164 4/20 0.63
ESRRG P62508 1/20 0.57
LY96 Q9Y6Y9 1/20 0.56
TRPV1 Q8NER1 1/20 0.56
LMNA P02545 2/20 0.54
PLAU P00749 1/20 0.53
POLB P06746 1/20 0.52
TSHR P16473 1/20 0.52
MAPK1 P28482 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29669668 1.00 RAB9A (0.67) RAB9ANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL28256407 0.82 RAB9A (0.76) RAB9ANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL29669746 0.82 RAB9A (0.76) RAB9ANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL3331071 0.78 RAB9A (0.74) RAB9ANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL12044291 0.77 NPC1 (0.57) RAB9ANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL3069128 0.76 RAB9A (0.71) RAB9ANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL3058851 0.76 KMT2A (0.69) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL8460943 0.76 RAB9A (0.75) RAB9ANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL3680858 0.76 KMT2A (0.71) RAB9ANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL20078361 0.76 RAB9A (0.83) RAB9ANPC1SMN1; SMN2NFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108863892-B Gallic acid methyl ester analogue containing amide structure and application thereof 温州医科大学 2022-04-05 CN disclosed
CN-108863892-A A kind of gallicin analog of amide containing structure and application 温州医科大学 2018-11-23 CN disclosed