Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 3/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.52 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.52 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.52 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.52 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.52 |
| ▸ | CDC25B | P30305 | 7/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.50 |
| ▸ | GJA1 | P17302 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3752571 | 0.97 | GJB2 (0.57) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL13058755 | 0.97 | GJB2 (0.57) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL13058729 | 0.97 | GJB2 (0.57) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL13058745 | 0.96 | GJB2 (0.58) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL13058741 | 0.96 | GJB2 (0.58) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL13058703 | 0.96 | GJB2 (0.58) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL13058715 | 0.96 | GJB2 (0.58) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL3758159 | 0.96 | GJB2 (0.58) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL3760613 | 0.96 | GJB2 (0.58) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL13058726 | 0.95 | GJB2 (0.54) | GJB2PTPN1PTPN2PTPN11NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2186818-A1 | Chemical synthesis of phosphatidylinositol mannoside glycans form mycobacterium tuberculosis | ETH Zurich (CH) | 2010-05-19 | — | — | EP | disclosed |