Phenol

Phenol

SCHEMBL28257274

CC(C)(C)c1ccc(C(C)(C)C)cc1.Oc1ccccc1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.75
TYR P14679 1/20 0.75
ESR1 P03372 4/20 0.62
ESR2 Q92731 4/20 0.62
ALDH1A1 P00352 4/20 0.62
CYP3A4 P08684 2/20 0.62
TDP1 Q9NUW8 3/20 0.58
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
GLA P06280 1/20 0.58
CA3 P07451 1/20 0.58
CA4 P22748 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58
TSHR P16473 2/20 0.52
HPGD P15428 2/20 0.52
HSD17B10 Q99714 2/20 0.52
AR P10275 1/20 0.52
SLC6A2 P23975 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL28166105 0.97 LMNA (0.80) LMNATYRESR1ESR2ALDH1A1
Phenol SCHEMBL875409 0.97 LMNA (0.80) LMNATYRESR1ESR2ALDH1A1
Tert-Butylbenzene SCHEMBL27389999 0.95 LMNA (0.67) LMNATYRESR1ESR2ALDH1A1
Tert-Butylbenzene SCHEMBL27701218 0.92 LMNA (0.64) LMNATYRESR1ESR2ALDH1A1
Phenol SCHEMBL27368426 0.91 TSHR (0.65) LMNATYRESR1ESR2ALDH1A1
Phenol SCHEMBL1876705 0.91 LMNA (0.70) LMNATYRESR1ESR2ALDH1A1
Tert-Butylbenzene SCHEMBL27837703 0.90 LMNA (0.61) LMNATYRESR1ESR2ALDH1A1
Phenol SCHEMBL27607408 0.89 LMNA (0.60) LMNATYRESR1ESR2ALDH1A1
Biphenyl SCHEMBL7702949 0.88 LMNA (0.73) LMNATYRESR1ESR2ALDH1A1
SCHEMBL20520408 0.88 LMNA (0.73) LMNATYRESR1ESR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105143160-B Bridged alkaline earth metal alkyl phenates 路博润公司 2018-11-20 CN disclosed