SCHEMBL28257552

SCHEMBL28257552

CO[Si](CC(Cl)CCl)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6141519 0.79 ALDH1A1 (0.30) TSHRTDP1
SCHEMBL9705066 0.76
SCHEMBL31142034 0.75 TP53 (0.31) TP53TSHRTDP1
SCHEMBL11370848 0.75
SCHEMBL9245791 0.75 TP53 (0.31) TP53TSHRTDP1
SCHEMBL31142021 0.75
SCHEMBL320162 0.74 MAPK1 (0.33) TSHR
SCHEMBL2110361 0.72
SCHEMBL27476009 0.72
SCHEMBL29740314 0.72 CA1 (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106062088-B Processed filler, the composition comprising the filler and the product prepared by the filler PPG工业俄亥俄公司 2018-12-07 CN claimed
EP-4691523-A1 MEDICAL INSTRUMENT, TREATMENT SOLUTION, AND METHOD FOR MANUFACTURING MEDICAL INSTRUMENT JMS Co., Ltd. (JP) 2026-02-11 EP disclosed
WO-2024204412-A1 MEDICAL INSTRUMENT, TREATMENT SOLUTION, AND METHOD FOR MANUFACTURING MEDICAL INSTRUMENT 株式会社ジェイ・エム・エス 2024-10-03 WO disclosed