SCHEMBL28257591

SCHEMBL28257591

C=C(C)C(=O)OC(C)O[Si](C)(CCCCCCCCCCC)OCC

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
LMNA P02545 3/20 0.33
FAAH O00519 1/20 0.31
MAPT P10636 1/20 0.31
ALDH1A1 P00352 1/20 0.31
THRB P10828 1/20 0.30
PRKCA P17252 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27679850 0.94 TSHR (0.37) TSHRTHRB
SCHEMBL691745 0.89 TSHR (0.35) TSHRTHRB
SCHEMBL28029517 0.88 TSHR (0.33) TSHRTHRB
SCHEMBL28211365 0.86 TSHR (0.42) TSHRLMNAFAAHTHRB
SCHEMBL27965470 0.86 TSHR (0.42) TSHRLMNAFAAHTHRB
SCHEMBL28097594 0.86 TSHR (0.42) TSHRLMNAFAAHTHRB
SCHEMBL27680762 0.84 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL27985882 0.81 TSHR (0.37) TSHRLMNAFAAHMAPTALDH1A1
SCHEMBL27985542 0.81 TSHR (0.37) TSHRLMNAFAAHMAPTALDH1A1
SCHEMBL28150384 0.81 TSHR (0.37) TSHRLMNAFAAHMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110819129-B Functional assembled magnesium-aluminum-based layered double-hydroxide modifier and preparation method and application thereof 福州大学 2022-06-24 CN claimed
CN-106700662-B Preparation method of acid-base-resistant anticorrosive aluminum pigment 安徽大学 2019-01-04 CN claimed
CN-110819129-B Functional assembled magnesium-aluminum-based layered double-hydroxide modifier and preparation method and application thereof 福州大学 2022-06-24 CN disclosed
CN-110819129-A Functional assembled magnesium-aluminum-based layered double-hydroxide modifier and preparation method and application thereof 福州大学 2020-02-21 CN disclosed