Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASH1L | Q9NR48 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12825335 | 0.80 | CCR4 (0.41) | HTR2CHTR2AHTR6CCR4 | |
| SCHEMBL14981465 | 0.79 | HTR2C (0.55) | ASH1LHTR2CHTR2ANR3C1PGR | |
| SCHEMBL14977330 | 0.79 | ASH1L (0.41) | ASH1LHTR2CHTR2ANR3C1PGR | |
| SCHEMBL29811286 | 0.79 | ASH1L (0.41) | ASH1LHTR2CHTR2ANR3C1PGR | |
| SCHEMBL30595498 | 0.79 | ASH1L (0.39) | ASH1LHTR2CHTR2ANR3C1PGR | |
| SCHEMBL30098925 | 0.76 | IDO1 (0.44) | ASH1LHTR6HTR3A | |
| SCHEMBL30098893 | 0.76 | HTR6 (0.42) | ASH1LHTR2CHTR2ANR3C1PGR | |
| SCHEMBL28826241 | 0.76 | HTR6 (0.60) | ASH1LHTR2CHTR2ANR3C1PGR | |
| SCHEMBL19260954 | 0.74 | KDM4E (0.43) | ASH1LNR3C1PGRNR3C2CYP1A2 | |
| SCHEMBL30098951 | 0.74 | HTR2C (0.36) | ASH1LHTR2CHTR2ANR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109069481-A | Methods and compounds for restoring function of mutant p53 | 皮姆维制药公司 | 2018-12-21 | — | — | CN | disclosed |