SCHEMBL28258381

SCHEMBL28258381

ClC(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)c1cccc2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.41
CYP1A2 P05177 4/20 0.41
ACP3 P15309 2/20 0.40
ALDH1A1 P00352 6/20 0.39
HSD17B10 Q99714 4/20 0.39
TSHR P16473 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPGD P15428 2/20 0.37
CYP3A4 P08684 1/20 0.37
KEAP1 Q14145 1/20 0.37
HPRT1 P00492 1/20 0.36
PAX8 Q06710 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP1B1 Q16678 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28256742 0.87 CYP1A2 (0.44) CYP2A6CYP1A2ACP3ALDH1A1HSD17B10
SCHEMBL18243792 0.78
SCHEMBL1538546 0.78 CYP2A6 (0.54) CYP2A6CYP1A2ACP3ALDH1A1HSD17B10
SCHEMBL18243961 0.77 PAX8 (0.38) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
SCHEMBL18241938 0.76
SCHEMBL11844876 0.74 CYP2A6 (0.44) CYP2A6CYP1A2ACP3ALDH1A1HSD17B10
SCHEMBL17966497 0.74 CYP2A6 (0.44) CYP2A6CYP1A2ACP3ALDH1A1HSD17B10
SCHEMBL8376830 0.74 ACP3 (0.45) CYP2A6CYP1A2ACP3ALDH1A1HSD17B10
SCHEMBL16933751 0.74 CYP2A6 (0.44) CYP2A6CYP1A2ACP3ALDH1A1HSD17B10
SCHEMBL17966537 0.74 CYP1A2 (0.44) CYP2A6CYP1A2ACP3ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105764885-B The production method of acid and free-radical generating agent and acid and free radical 富士胶片和光纯药株式会社 2018-11-09 CN disclosed