SCHEMBL28258463

SCHEMBL28258463

NN=C(Nc1ccccc1)Nc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS2R38 P59533 3/20 0.50
HSD17B10 Q99714 3/20 0.50
ALDH1A1 P00352 3/20 0.50
TP53 P04637 2/20 0.50
TSHR P16473 2/20 0.50
TYR P14679 1/20 0.50
KMT2A Q03164 3/20 0.48
GRIN2D O15399 1/20 0.48
GRIN3B O60391 1/20 0.48
LMNA P02545 1/20 0.48
CYP2D6 P10635 1/20 0.48
SLC6A2 P23975 1/20 0.48
GRIN1 Q05586 1/20 0.48
GRIN2A Q12879 1/20 0.48
GRIN2B Q13224 1/20 0.48
GRIN2C Q14957 1/20 0.48
GRIN3A Q8TCU5 1/20 0.48
SIGMAR1 Q99720 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
EPHX1 P07099 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL9415818 0.87 KMT2A (0.44) TAS2R38HSD17B10ALDH1A1TP53TSHR
Iodide SCHEMBL9415820 0.87 KMT2A (0.44) TAS2R38HSD17B10ALDH1A1TP53TSHR
SCHEMBL11655504 0.78 GRIN2D (0.63) TAS2R38HSD17B10ALDH1A1TP53TSHR
SCHEMBL10625419 0.78 GRIN2D (0.63) TAS2R38HSD17B10ALDH1A1TP53TSHR
SCHEMBL21699678 0.78 TAS2R38 (0.48) TAS2R38HSD17B10ALDH1A1TP53TSHR
SCHEMBL871606 0.77 TAS2R38 (0.50) TAS2R38HSD17B10ALDH1A1TP53TSHR
SCHEMBL11184467 0.75 TAS2R38 (0.50) TAS2R38HSD17B10ALDH1A1TP53TSHR
SCHEMBL78799 0.73 KMT2A (0.63) TAS2R38HSD17B10ALDH1A1TP53TSHR
SCHEMBL21937249 0.73 IDO1 (0.42) ALDH1A1KMT2ACYP1A2
Hydrochloric Acid SCHEMBL3143816 0.71 KMT2A (0.61) TAS2R38HSD17B10ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111117272-A Low-temperature-resistant modified asphalt pavement repairing material and preparation method thereof 福建师范大学 2020-05-08 CN disclosed
CN-109369324-A The method of dehydrochlorination for chlorinated hydrocabon 索尔维特殊聚合物意大利有限公司 2019-02-22 CN disclosed
CN-105452201-B Process for dehydrochlorination of chlorinated hydrocarbons 索尔维特殊聚合物意大利有限公司 2018-11-23 CN disclosed