Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728738 | 0.89 | KMT2A (0.64) | MMP8KMT2APIN1CHRM2CHRM4 | |
| SCHEMBL28497599 | 0.87 | MMP8 (0.54) | MMP8KMT2APIN1CHRM2CHRM4 | |
| SCHEMBL1661290 | 0.87 | MMP8 (0.54) | MMP8KMT2APIN1CHRM2CHRM4 | |
| SCHEMBL25600199 | 0.86 | MMP8 (0.53) | MMP8KMT2APIN1CHRM2CHRM4 | |
| SCHEMBL1645937 | 0.84 | MMP8 (0.51) | MMP8KMT2APIN1CHRM2CHRM4 | |
| SCHEMBL27629137 | 0.84 | MMP8 (0.51) | MMP8KMT2APIN1CHRM2CHRM4 | |
| SCHEMBL1646940 | 0.84 | MMP8 (0.51) | MMP8KMT2APIN1CHRM2CHRM4 | |
| SCHEMBL13751893 | 0.84 | MMP8 (0.54) | MMP8KMT2APIN1MEN1NPC1 | |
| SCHEMBL9225532 | 0.84 | MMP8 (0.54) | MMP8KMT2APIN1MEN1NPC1 | |
| SCHEMBL2301980 | 0.84 | MMP8 (0.54) | MMP8KMT2APIN1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053861-A | A kind of preparation method of Carfilzomib | 上海雅本化学有限公司 | 2018-12-21 | — | — | CN | disclosed |