SCHEMBL28259253

SCHEMBL28259253

CCCC(O)c1ccccc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
ALOX15 P16050 1/20 0.50
KDM4E B2RXH2 3/20 0.45
TAAR1 Q96RJ0 1/20 0.45
KMT2A Q03164 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
GAA P10253 1/20 0.45
MEN1 O00255 1/20 0.44
RECQL P46063 1/20 0.44
MAPT P10636 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
TSHR P16473 1/20 0.41
POLB P06746 1/20 0.41
AKR1C3 P42330 2/20 0.41
LMNA P02545 1/20 0.41
CA12 O43570 2/20 0.41
CA9 Q16790 2/20 0.41
MYC P01106 1/20 0.40
NR4A1 P22736 1/20 0.40
CA1 P00915 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23521275 0.91 KMT2A (0.50) ALDH1A1ALOX15KDM4EKMT2ATDP1
SCHEMBL29360777 0.91 KMT2A (0.50) ALDH1A1ALOX15KDM4EKMT2ATDP1
SCHEMBL1935639 0.91 KMT2A (0.50) ALDH1A1ALOX15KDM4EKMT2ATDP1
SCHEMBL23521291 0.91 KMT2A (0.50) ALDH1A1ALOX15KDM4EKMT2ATDP1
SCHEMBL29869129 0.91 KMT2A (0.50) ALDH1A1ALOX15KDM4EKMT2ATDP1
SCHEMBL1934052 0.90 KMT2A (0.49) ALDH1A1ALOX15KDM4EKMT2ATDP1
Ammonia Solution, Strong SCHEMBL29034511 0.90 KMT2A (0.49) ALDH1A1ALOX15KDM4EKMT2ATDP1
SCHEMBL3122937 0.90 KMT2A (0.49) ALDH1A1ALOX15KDM4EKMT2ATDP1
Potassium SCHEMBL31438078 0.90 KMT2A (0.49) ALDH1A1ALOX15KDM4EKMT2ATDP1
SCHEMBL5435365 0.90 KMT2A (0.49) ALDH1A1ALOX15KDM4EKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108947946-B Brain injury resistant deuterated compound and medical application thereof 泰州华元医药科技有限公司 2022-10-28 CN disclosed
CN-108947946-A Anti- cerebral injury deuterated compound and its medical usage 泰州华元医药科技有限公司 2018-12-07 CN disclosed