Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1935639 | 0.98 | KMT2A (0.50) | KMT2AKDM4EMEN1RECQLALDH1A1 | |
| SCHEMBL23521275 | 0.98 | KMT2A (0.50) | KMT2AKDM4EMEN1RECQLALDH1A1 | |
| SCHEMBL29869129 | 0.98 | KMT2A (0.50) | KMT2AKDM4EMEN1RECQLALDH1A1 | |
| SCHEMBL23521291 | 0.98 | KMT2A (0.50) | KMT2AKDM4EMEN1RECQLALDH1A1 | |
| SCHEMBL29360777 | 0.98 | KMT2A (0.50) | KMT2AKDM4EMEN1RECQLALDH1A1 | |
| Potassium SCHEMBL31438078 | 0.97 | KMT2A (0.49) | KMT2AKDM4EMEN1RECQLALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL29034511 | 0.97 | KMT2A (0.49) | KMT2AKDM4EMEN1RECQLALDH1A1 | |
| SCHEMBL3122937 | 0.97 | KMT2A (0.49) | KMT2AKDM4EMEN1RECQLALDH1A1 | |
| SCHEMBL5435365 | 0.97 | KMT2A (0.49) | KMT2AKDM4EMEN1RECQLALDH1A1 | |
| Tert-Butylamine SCHEMBL31072748 | 0.91 | KMT2A (0.44) | KMT2AKDM4EMEN1RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110224300-A1 | USE OF POTASSIUM 2-(a- HYDROXYPENTYL) BENZOATE IN THE MANUFACTURE OF MEDICAMENTS FOR PREVENTING AND/OR TREATING SENILE DEMENTIA | INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF ME (CN) | 2011-09-15 | — | — | US | claimed |
| EP-2332530-A1 | THE USE OF POTASSIUM 2-( - HYDROXYPENTYL) BENZOATE IN THE MANUFACTURE OF MEDICAMENTS FOR PREVENTING AND/OR TREATING SENILE DEMENTIA | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2011-06-15 | — | — | EP | claimed |
| CN-115932126-A | Detection method for measuring racemization-3-n-butylphthalide related substances by HPLC | 河北菲尼斯生物技术有限公司 | 2023-04-07 | — | — | CN | disclosed |
| EP-3023410-B1 | 5-BROMINE-2-(alpha-HYDROXYPENTYL)BENZOIC ACID SODIUM SALTS IN DIFFERENT CRYSTAL FORMS, AND PREPARATION METHOD THEREOF | ZHEJIANG AUSUN PHARMACEUTICAL CO LTD (CN) | 2022-02-23 | — | — | EP | disclosed |
| US-11148991-B2 | 5-bromo-2-(alpha-hydroxypentyl)benzoic acid sodium salts in different crystal forms, and preparation method thereof | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2021-10-19 | — | — | US | disclosed |
| US-11149005-B2 | Organic amine ester derivative drug of 2-(α-hydroxypentyl)benzoic acid | YAOPHARMA CO., LTD. (CN) | 2021-10-19 | — | — | US | disclosed |
| US-11028073-B2 | Butylphthalide-telmisartan hybrids, preparation method and application thereof | GUANGDONG LONGFU MEDICINE CO., LTD. (CN) | 2021-06-08 | — | — | US | disclosed |
| CN-112608226-A | Synthesis method of hydroxypentyl potassium benzoate D7 | 云南昊邦制药有限公司 | 2021-04-06 | — | — | CN | disclosed |
| US-20210002224-A1 | ORGANIC AMINE ESTER DERIVATIVE DRUG OF 2-(alpha-HYDROXYPENTYL)BENZOIC ACID | SICHUAN UNIVERSITY (CN) | 2021-01-07 | — | — | US | disclosed |
| EP-3760610-A1 | ORGANIC AMINE ESTER DERIVATIVE DRUG OF 2-(A-HYDROXYPENTYL)BENZOIC ACID | Sichuan University (CN) | 2021-01-06 | — | — | EP | disclosed |
| EP-3572404-B1 | BUTYLPHTHALIDE-TELMISARTAN HETEROCOMPLEX, PREPARATION METHOD AND APPLICATION THEREOF | GUANGDONG LONGFU MEDICINE CO LTD (CN) | 2020-10-21 | — | — | EP | disclosed |
| EP-1508561-B1 | 2-(a-HYDROXYPENTYL) BENZOATE AND ITS PREPARATION AND USE | INST OF MATERIA MEDICA OF CHIN (CN) | 2009-09-23 | — | — | EP | disclosed |
| US-20090227809-A1 | NEW 2-(ALPHA-HYDROXYPENTYL) BENZOATES, THEIR PREPARATIONS AND THEIR USES | THE INSTITUTE OF MATERIA MEDICA OF CHINESE ACADEMY OF MEDICAL SCIENCES. | 2009-09-10 | — | — | US | disclosed |
| US-7550507-B2 | 2-(alpha-hydroxypentyl) benzoate and its preparation and use | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2009-06-23 | — | — | US | disclosed |
| US-20070203233-A1 | NOVEL 2-(alpha-N-PENTANONYL)BENZOATES, THEIR PREPARATION AND USE | TEAM ACADEMY OF PHARMACEUTICAL SCIENCE (CN) | 2007-08-30 | — | — | US | disclosed |
| EP-1734031-A1 | NOVEL 2-(ALPHA-N-PENTANONYL)BENZOETES, THEIR PREPARATION AND USE | TEAM ACADEMY OF PHARMACEUTICAL SCIENCE (CN) | 2006-12-20 | — | — | EP | disclosed |
| CN-1243541-C | 2-(alpha-hydroxypentyl) benzoate and its preparing process and usage | INST MATERIA MEDICA CAMS (CN) | 2006-03-01 | — | — | CN | disclosed |
| US-20050288263-A1 | dosage forms of benzoate salt such as sodium, calcium, or amine salts; cardioischemia, cerebroischemia and cardiac or cerebral arterial occlusion | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES, THE (CN) | 2005-12-29 | — | — | US | disclosed |
| EP-1508561-A1 | 2-(a-HYDROXYPENTYL) BENZOATE AND ITS PREPARATION AND USE | THE INSTITUTE OF MATERIA MEDICA OF CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2005-02-23 | — | — | EP | disclosed |
| CN-1382682-A | 2-(alpha-hydroxypentyl) benzoate and its preparing process and usage | INST OF MEDICAL MATERIALS CHIN (CN) | 2002-12-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11149005-B2 | Organic amine ester derivative drug of 2-(α-hydroxypentyl)benzoic acid | DBH, PARK7, SNCA | KMT2A 2985/4885KDM4E 1984/4885MEN1 2600/4885 |
| US-20110224300-A1 | USE OF POTASSIUM 2-(a- HYDROXYPENTYL) BENZOATE IN THE MANUFACTURE OF MEDICAMENTS FOR PREVENTING AND/OR TREATING SENILE DEMENTIA | BDNF, NGF, ACHE | KMT2A 649/4885KDM4E 334/4885MEN1 2533/4885 |
| US-20090227809-A1 | NEW 2-(ALPHA-HYDROXYPENTYL) BENZOATES, THEIR PREPARATIONS AND THEIR USES | HIF1AN, HAAO, HIF1A | KMT2A 3476/4885KDM4E 2996/4885MEN1 4258/4885 |
| US-20050288263-A1 | dosage forms of benzoate salt such as sodium, calcium, or amine salts; cardioischemia, cerebroischemia and cardiac or cerebral arterial occlusion | CA2, SLC8B1, HAO2 | KMT2A 1581/4885KDM4E 1676/4885MEN1 3358/4885 |
| US-11028073-B2 | Butylphthalide-telmisartan hybrids, preparation method and application thereof | AGT, AGTR1, ACE | KMT2A 4711/4885KDM4E 4499/4885MEN1 1750/4885 |
| US-11148991-B2 | 5-bromo-2-(alpha-hydroxypentyl)benzoic acid sodium salts in different crystal forms, and preparation method thereof | GABRA5, NPY5R, SLC9A5 | KMT2A 1286/4885KDM4E 921/4885MEN1 4214/4885 |
| US-20070203233-A1 | NOVEL 2-(alpha-N-PENTANONYL)BENZOATES, THEIR PREPARATION AND USE | TBXA2R, TBXAS1, PFKP | KMT2A 4657/4885KDM4E 3521/4885MEN1 2742/4885 |
| US-20210002224-A1 | ORGANIC AMINE ESTER DERIVATIVE DRUG OF 2-(alpha-HYDROXYPENTYL)BENZOIC ACID | DBH, PARK7, SNCA | KMT2A 2959/4885KDM4E 2063/4885MEN1 2560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.