SCHEMBL28259386

SCHEMBL28259386

C=CCOC(=O)n1cc(CCN)c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.46
HTR6 P50406 12/20 0.42
CYP3A4 P08684 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
SCN9A Q15858 1/20 0.41
BLM P54132 1/20 0.39
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB1 P18505 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
GABRA2 P47869 1/20 0.38
GABRB2 P47870 1/20 0.38
GABRA4 P48169 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9116988 0.81 TACR3 (0.49) HTR2AHTR6L3MBTL1SCN9A
SCHEMBL8802724 0.79 HTR2A (0.45) HTR2AHTR6L3MBTL1ALDH1A1HSD17B10
SCHEMBL10824174 0.79 OXER1 (0.49) HTR2AHTR6CYP3A4L3MBTL1ALDH1A1
SCHEMBL27721427 0.78 HTR2A (0.58) HTR2AHTR6SCN9A
SCHEMBL29992401 0.77 L3MBTL1 (0.65) HTR2AHTR6L3MBTL1SCN9AEPHX1
SCHEMBL7505969 0.77 L3MBTL1 (0.65) HTR2AHTR6L3MBTL1SCN9AEPHX1
SCHEMBL5304010 0.77 HTR2A (0.57) HTR2AHTR6ALDH1A1SCN9A
SCHEMBL627039 0.77 HTR2A (0.57) HTR2AHTR6CYP3A4SCN9A
SCHEMBL29424269 0.76 HTR2A (0.59) HTR2AHTR6ALDH1A1SCN9A
Hydrochloric Acid SCHEMBL8648129 0.76 HTR2A (0.55) HTR2AHTR6SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108997352-A It can be seen that the method for light-initiated asymmetric syntheses 3- nitrogen oxygroup pyrroles [2,3-b] Benzazole compounds 云南大学 2018-12-14 CN disclosed