Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.74 |
| ▸ | CA2 | P00918 | 7/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | STAT3 | P40763 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14372330 | 0.90 | MEN1 (0.76) | CA1CA2NPC1RAB9AMEN1 | |
| SCHEMBL14372362 | 0.84 | CA1 (0.77) | CA1CA2MEN1KMT2AALDH1A1 | |
| SCHEMBL28261098 | 0.80 | MAPT (0.69) | CA1CA2NPC1RAB9AMEN1 | |
| SCHEMBL939934 | 0.80 | CA1 (0.67) | CA1CA2NPC1RAB9AMEN1 | |
| SCHEMBL13764406 | 0.79 | MEN1 (0.76) | CA1CA2NPC1RAB9AMEN1 | |
| SCHEMBL14372397 | 0.79 | MEN1 (0.67) | CA1CA2NPC1RAB9AMEN1 | |
| SCHEMBL14372404 | 0.79 | CA1 (1.00) | CA1CA2NPC1RAB9AMEN1 | |
| SCHEMBL14372369 | 0.79 | CA1 (0.76) | CA1CA2MEN1KMT2ACA9 | |
| SCHEMBL14372342 | 0.79 | CA1 (0.71) | CA1CA2NPC1RAB9AMEN1 | |
| SCHEMBL14372339 | 0.78 | CA2 (0.70) | CA1CA2RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997176-B | 4-chloro-N-substituted phenyl-3-sulfonyl aminobenzamide compound, and preparation and anti-tumor application thereof | 温州医科大学 | 2021-07-02 | — | — | CN | disclosed |
| CN-108997176-A | A kind of chloro- N- substituted-phenyl -3- sulphonamidobenzamide class compound of 4- and its preparation and antitumor application thereof | 温州医科大学 | 2018-12-14 | — | — | CN | disclosed |