Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acridine SCHEMBL28191835 | 0.88 | ALDH1A1 (0.62) | ALDH1A1HPGDMAPTACHEGLA | |
| Acridine SCHEMBL27575353 | 0.86 | ALDH1A1 (0.65) | ALDH1A1HPGDMAPTACHEGLA | |
| Acridine SCHEMBL27575378 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HPGDMAPTACHEGLA | |
| Carbazole SCHEMBL28326877 | 0.82 | ALDH1A1 (0.67) | ALDH1A1HPGDACHEGLAGPR3 | |
| Carbazole SCHEMBL27609620 | 0.82 | ALDH1A1 (0.67) | ALDH1A1HPGDACHEGLAGPR3 | |
| Carbazole SCHEMBL28311656 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HPGDACHEGPR3HSD17B10 | |
| Acridine SCHEMBL28002070 | 0.77 | AHR (0.55) | ALDH1A1HPGDMAPTACHEGLA | |
| Phenazine SCHEMBL6742600 | 0.76 | ALDH1A1 (0.70) | ALDH1A1HPGDMAPTACHEGLA | |
| Carbazole SCHEMBL28074860 | 0.76 | PARP1 (0.44) | ALDH1A1HPGDMAPTACHEGPR3 | |
| Anthracene SCHEMBL5607729 | 0.74 | ALDH1A1 (0.74) | ALDH1A1HPGDMAPTACHEGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108948010-A | It is a kind of based on acridine-azepine carbazole unit compound and its application | 瑞声科技（南京）有限公司 | 2018-12-07 | — | — | CN | claimed |
| CN-108948010-A | It is a kind of based on acridine-azepine carbazole unit compound and its application | 瑞声科技（南京）有限公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-108948010-A | It is a kind of based on acridine-azepine carbazole unit compound and its application | 瑞声科技（南京）有限公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-108948010-A | It is a kind of based on acridine-azepine carbazole unit compound and its application | 瑞声科技（南京）有限公司 | 2018-12-07 | — | — | CN | disclosed |