Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830144 | 0.87 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL2822532 | 0.82 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL2828162 | 0.71 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL2828163 | 0.71 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL25422729 | 0.67 | CYP2C9 (0.30) | — | |
| SCHEMBL2827381 | 0.66 | HSD11B1 (0.48) | HSD11B1 | |
| SCHEMBL2022323 | 0.62 | HSD11B1 (0.60) | HSD11B1 | |
| SCHEMBL1622891 | 0.59 | AKR1C1 (0.47) | HSD11B1AKR1C1 | |
| SCHEMBL2027589 | 0.58 | HSD11B1 (0.57) | HSD11B1AKR1C1 | |
| Hydrochloric Acid SCHEMBL28933139 | 0.57 | AKR1C1 (0.45) | HSD11B1AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243479-A2 | Novel amide and amidine derivates and uses thereof | Abbott Laboratories (US) | 2010-10-27 | — | — | EP | claimed |
| US-20100267738-A1 | NOVEL AMIDE AND AMIDINE DERIVATIVES AND USES THEREOF | ABBOTT LABORATORIES (US) | 2010-10-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267738-A1 | NOVEL AMIDE AND AMIDINE DERIVATIVES AND USES THEREOF | HSD11B2, HSD11B1, HSD17B2 | HSD11B1 2/4885AKR1C1 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.