Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | FCER2 | P06734 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 5/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 2/20 | 0.45 |
| ▸ | CPA3 | P15088 | 2/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433211 | 0.86 | CYP1A2 (0.61) | MMP1FCER2CYP1A2MMELTA4H | |
| SCHEMBL9531957 | 0.85 | CYP1A2 (0.55) | CYP1A2MMELTA4HCPA1CPA3 | |
| SCHEMBL490150 | 0.82 | CYP1A2 (0.52) | CYP1A2MEN1KMT2ACPA1ALDH1A1 | |
| SCHEMBL490152 | 0.82 | CYP1A2 (0.52) | CYP1A2MEN1KMT2ACPA1ALDH1A1 | |
| SCHEMBL2396464 | 0.81 | CYP1A2 (0.70) | CYP1A2MMECPA1CPA3FOLH1 | |
| SCHEMBL23732350 | 0.80 | CYP1A2 (0.53) | MMP1FCER2CYP1A2MMELTA4H | |
| SCHEMBL563663 | 0.76 | PPARG (0.53) | CYP1A2MEN1KMT2ANPC1CPA1 | |
| SCHEMBL7418989 | 0.75 | MMP3 (0.61) | MMP1 | |
| SCHEMBL6469693 | 0.74 | MEN1 (0.56) | MMP1FCER2MEN1KMT2A | |
| SCHEMBL19033467 | 0.74 | MEN1 (0.56) | MMP1FCER2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829305-B | NRF2 regulator | 葛兰素史密斯克莱知识产权发展有限公司 | 2018-11-30 | — | — | CN | disclosed |