Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68056 | 0.89 | MAPK1 (1.00) | MAPK1GAAALPLMAPTRAB9A | |
| SCHEMBL30614240 | 0.87 | MAPK1 (0.96) | MAPK1GAAALPLMAPTRAB9A | |
| SCHEMBL1812854 | 0.85 | MAPK1 (0.79) | MAPK1GAAALPLMAPTRAB9A | |
| SCHEMBL1267225 | 0.85 | MAPK1 (0.79) | MAPK1GAAHCAR2DAOALPL | |
| SCHEMBL20489052 | 0.82 | MAPK1 (0.74) | MAPK1GAAALPLMAPTRAB9A | |
| SCHEMBL285996 | 0.81 | MAPK1 (0.67) | MAPK1GAAALPLMAPTRAB9A | |
| SCHEMBL1814464 | 0.81 | MAPK1 (0.72) | MAPK1GAAALPLMAPTRAB9A | |
| SCHEMBL70577 | 0.80 | HCAR2 (0.59) | MAPK1HCAR2DAOALPLHCAR3 | |
| SCHEMBL30107039 | 0.79 | MAPK1 (0.70) | MAPK1GAAALPLMAPTRAB9A | |
| SCHEMBL12168148 | 0.79 | HCAR2 (0.59) | MAPK1HCAR2DAOHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4117784-A1 | GPR52 MODULATOR COMPOUNDS | Heptares Therapeutics Limited (GB) | 2023-01-18 | — | — | EP | disclosed |
| CN-109071468-A | Heterocyclic compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2018-12-21 | — | — | CN | disclosed |