Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554887 | 0.81 | DHFR (0.32) | HRH4NR1H2NR1H3TAAR1DHFR | |
| SCHEMBL2082690 | 0.80 | TAAR1 (0.55) | TAAR1 | |
| SCHEMBL29920692 | 0.80 | TAAR1 (0.55) | TAAR1 | |
| SCHEMBL2082689 | 0.80 | TAAR1 (0.55) | TAAR1 | |
| SCHEMBL171090 | 0.77 | HRH4 (0.40) | HRH4NR1H2NR1H3DHFRCRHR1 | |
| SCHEMBL8160812 | 0.76 | HRH4 (0.36) | HRH4TAAR1CRHR1 | |
| SCHEMBL165551 | 0.67 | PRMT1 (0.38) | HRH4NR1H2NR1H3DHFR | |
| SCHEMBL2080265 | 0.67 | TAAR1 (0.50) | TAAR1 | |
| SCHEMBL2080261 | 0.67 | TAAR1 (0.50) | TAAR1 | |
| SCHEMBL23549985 | 0.66 | DHFR (0.39) | HRH4DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071518-A | Oxazoline vacation dimer, medical composition and its use | 普渡制药公司 | 2018-12-21 | — | — | CN | disclosed |