Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28185172 | 0.82 | CYP19A1 (0.61) | CYP19A1CYP1B1CYP17A1MEN1LMNA | |
| SCHEMBL4885211 | 0.81 | CYP19A1 (0.67) | CYP19A1CYP1B1MEN1LMNASHBG | |
| SCHEMBL606825 | 0.81 | CYP19A1 (0.67) | CYP19A1CYP1B1MEN1LMNASHBG | |
| SCHEMBL32677703 | 0.81 | CYP19A1 (0.67) | CYP19A1CYP1B1MEN1LMNASHBG | |
| SCHEMBL26807214 | 0.81 | CYP19A1 (0.67) | CYP19A1CYP1B1MEN1LMNASHBG | |
| SCHEMBL28263239 | 0.80 | CYP19A1 (0.72) | CYP19A1CYP1B1CYP17A1MEN1LMNA | |
| SCHEMBL10404116 | 0.79 | CYP19A1 (0.57) | CYP19A1CYP1B1CYP17A1SHBG | |
| SCHEMBL10404115 | 0.79 | CYP19A1 (0.57) | CYP19A1CYP1B1CYP17A1SHBG | |
| SCHEMBL5489880 | 0.79 | CYP19A1 (0.54) | CYP19A1CYP1B1CYP17A1 | |
| SCHEMBL514563 | 0.79 | CYP19A1 (0.54) | CYP19A1CYP1B1CYP17A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109293727-A | 1- methyl purine -4- methylenandrosta-triazole derivatives, its synthetic method and application | 郑州大学 | 2019-02-01 | — | — | CN | disclosed |
| CN-109232703-A | Containing 16- (1 '-aromatic radical -1 ', 2 ', 3 '-triazoles) methylene-androstane -17- ketone derivatives | 郑州大学 | 2019-01-18 | — | — | CN | disclosed |