SCHEMBL606825

SCHEMBL606825

C[C@@]12CCC[C@H]1[C@@H]1CC=C3CCCC[C@]3(C)[C@H]1CC2

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 11/20 0.67
CYP1B1 Q16678 1/20 0.60
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
SHBG P04278 1/20 0.44
SERPINA6 P08185 1/20 0.44
GUSB P08236 1/20 0.44
CYP3A4 P08684 1/20 0.44
G6PD P11413 1/20 0.44
PMP22 Q01453 1/20 0.44
KMT2A Q03164 1/20 0.44
GPBAR1 Q8TDU6 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26807214 1.00 CYP19A1 (0.67) CYP19A1CYP1B1MEN1LMNASHBG
SCHEMBL4885211 1.00 CYP19A1 (0.67) CYP19A1CYP1B1MEN1LMNASHBG
SCHEMBL32677703 1.00 CYP19A1 (0.67) CYP19A1CYP1B1MEN1LMNASHBG
SCHEMBL28117691 0.90 CYP19A1 (0.56) CYP19A1CYP1B1
SCHEMBL1316417 0.82 CYP19A1 (0.45) CYP19A1CYP1B1MEN1LMNASHBG
SCHEMBL4448210 0.82 CYP17A1 (0.46) CYP19A1MEN1LMNASHBGSERPINA6
SCHEMBL1316415 0.82 CYP19A1 (0.45) CYP19A1CYP1B1MEN1LMNASHBG
SCHEMBL19818388 0.81 CYP17A1 (0.65) CYP19A1CYP1B1MEN1LMNASHBG
SCHEMBL29688903 0.81 CYP17A1 (0.65) CYP19A1CYP1B1MEN1LMNASHBG
SCHEMBL4448216 0.81 CYP19A1 (0.61) CYP19A1CYP1B1MEN1LMNASHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4232021-B1 SULFATED C19 STEROID HORMONES TO TREAT AND/OR PREVENT PROTEOTOXICITY IN PROTEIN-AGGREGATION DISEASES UNIV PABLO DE OLAVIDE (ES) 2026-05-27 EP claimed
CN-119595611-A Method for rapidly detecting androgenic steroid based on surface enhanced Raman scattering technology and application thereof 上海体育大学 2025-03-11 CN claimed
US-20230405020-A1 SULFATED C19 STEROID HORMONES TO TREAT AND/OR PREVENT PROTEOTOXICITY IN PROTEIN-AGGREGATION DISEASES UNIVERSIDAD PABLO DE OLAVIDE (ES) 2023-12-21 US claimed
CN-116916912-A Protein toxicity of sulfated C19 steroid hormone for treatment and/or prevention of protein aggregation disease 帕布罗·德奥拉韦德大学 2023-10-20 CN claimed
WO-2022149929-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING STEROID SULFATASE INHIBITOR 연세대학교 산학협력단 2022-07-14 WO claimed
US-20220193095-A9 PHARMACEUTICAL COMPOSITIONS Shenzhen Pharmacin Co., Ltd. (CN) 2022-06-23 US claimed
EP-3988096-A1 SULFATED C19 STEROID HORMONES TO TREAT AND/OR PREVENT PROTEOTOXICITY IN PROTEIN-AGGREGATION DISEASES Universidad Pablo de Olavide OTRI (ES) 2022-04-27 EP claimed
US-20200237784-A1 PHARMACEUTICAL COMPOSITIONS SHENZHEN PHARMACIN CO LTD (CN) 2020-07-30 US claimed
US-20160361244-A1 USE OF THE INHIBITOR OF STEROID SULFATASES STX64 FOR TREATING AGING UNIVERSIDAD PABLO DE OLAVIDE (ES) 2016-12-15 US claimed
EP-3011950-A1 USE OF THE INHIBITOR OF STEROID SULFATASES STX64 FOR TREATING AGING Universidad Pablo de Olavide (ES) 2016-04-27 EP claimed
EP-1083904-A2 PHARMACEUTICAL COMPOSITIONS AND USES FOR ANDROST-5-ENE-3 BETA,17 BETA-DIOL Endorecherche Inc. (CA) 2001-03-21 EP claimed
WO-2001001969-A2 METHODS OF TREATING AND/OR SUPPRESSING WEIGHT GAIN ENDORECHERCHE, INC. (CA) 2001-01-11 WO claimed
WO-2000020007-A1 METHOD AND COMPOSITIONS FOR INCREASING BONE MASS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2000-04-13 WO claimed
WO-1999063973-A2 PHARMACEUTICAL COMPOSITIONS AND USES FOR ANDROST-5-ENE-3β,17β-DIOL ENDORECHERCHE, INC. (CA) 1999-12-16 WO claimed
EP-0633893-B1 17-SUBSTITUTED STEROIDS USEFUL IN CANCER TREATMENT BTG INT LTD (GB) 1999-11-24 EP claimed
WO-1998056386-A1 A MEDICAMENT USEFUL FOR THE TREATMENT OF POST-MENOPAUSAL SYNDROME AND OSTEOPOROSIS, AND FOR REDUCING FAT MASS AND INCREASING LEAN BODY MASS SUNNIMEX LIMITED (GB) 1998-12-17 WO claimed
JP-2742331-B2 1998-04-22 JP claimed
EP-0633893-A1 17-SUBSTITUTED STEROIDS USEFUL IN CANCER TREATMENT BRITISH TECHNOLOGY GROUP LTD (GB) 1995-01-18 EP claimed
US-5277907-A Lymphocyte proliferation-enhancing agent VIRGINIA COMMONWEALTH UNIVERSITY (US) 1994-01-11 US claimed
WO-1993020097-A1 17-SUBSTITUTED STEROIDS USEFUL IN CANCER TREATMENT BRITISH TECHNOLOGY GROUP LTD. (GB) 1993-10-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220193095-A9 PHARMACEUTICAL COMPOSITIONS LIPA, LIPC, MGLL CYP19A1 674/4885CYP1B1 1092/4885MEN1 2842/4885
US-20230405020-A1 SULFATED C19 STEROID HORMONES TO TREAT AND/OR PREVENT PROTEOTOXICITY IN PROTEIN-AGGREGATION DISEASES SERPINA6, HTT, PSMG3 CYP19A1 1368/4885CYP1B1 4014/4885MEN1 1182/4885
US-20200237784-A1 PHARMACEUTICAL COMPOSITIONS LIPA, LIPC, MGLL CYP19A1 674/4885CYP1B1 1092/4885MEN1 2842/4885
US-20160361244-A1 USE OF THE INHIBITOR OF STEROID SULFATASES STX64 FOR TREATING AGING STS, CYP17A1, SCLY CYP19A1 101/4885CYP1B1 877/4885MEN1 3078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.