Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29355369 | 0.93 | EGFR (0.34) | EGFRPIK3CG | |
| SCHEMBL7626 | 0.93 | EGFR (0.34) | EGFRPIK3CG | |
| SCHEMBL28134927 | 0.91 | EGFR (0.33) | EGFRPIK3CG | |
| Potassium SCHEMBL29619940 | 0.91 | EGFR (0.33) | EGFRPIK3CG | |
| Hydrochloric Acid SCHEMBL27567069 | 0.91 | EGFR (0.33) | EGFRPIK3CG | |
| SCHEMBL27705809 | 0.91 | EGFR (0.33) | EGFRPIK3CG | |
| Phosphine SCHEMBL3090397 | 0.91 | CHRNB4 (0.33) | EGFRPIK3CG | |
| Hydrogen Sulfide SCHEMBL29184284 | 0.91 | EGFR (0.33) | EGFRPIK3CG | |
| Ammonia Solution, Strong SCHEMBL27506828 | 0.91 | EGFR (0.33) | EGFRPIK3CG | |
| Bromide SCHEMBL9315292 | 0.91 | EGFR (0.33) | EGFRPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071542-A | CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS | 凤凰分子设计公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-102421779-A | Dihydropteridinone derivatives, preparation method and pharmaceutical use thereof | JIANGSU HENGRUI MEDICINE CO | 2012-04-18 | — | — | CN | disclosed |
| CN-102421778-A | Dihydropteridinone derivatives, preparation process and pharmaceutical use thereof | JIANGSU HENGRUI MEDICINE CO | 2012-04-18 | — | — | CN | disclosed |