SCHEMBL28264261

SCHEMBL28264261

O=C1c2cc([N+](=O)[O-])ccc2-c2cccc(I)c21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 3/20 0.64
S100A4 P26447 2/20 0.64
BCHE P06276 1/20 0.64
ACHE P22303 1/20 0.64
CES1 P23141 1/20 0.64
MAPT P10636 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
CYP1A2 P05177 1/20 0.50
HIF1A Q16665 1/20 0.50
HSD17B10 Q99714 1/20 0.50
ALDH1A1 P00352 1/20 0.49
HSP90AA1 P07900 1/20 0.47
CDK5 Q00535 1/20 0.47
CDK5R1 Q15078 1/20 0.47
NCOA1 Q15788 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47
CYP3A4 P08684 1/20 0.45
CA12 O43570 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28315490 0.82 PTPRC (0.64) PTPRCS100A4BCHEACHECES1
SCHEMBL31615476 0.79 PTPRC (0.93) PTPRCS100A4BCHEACHECES1
SCHEMBL229511 0.79 PTPRC (0.93) PTPRCS100A4BCHEACHECES1
SCHEMBL30096355 0.79 PTPRC (1.00) PTPRCS100A4BCHEACHECES1
SCHEMBL2599395 0.79 PTPRC (1.00) PTPRCS100A4BCHEACHECES1
SCHEMBL4586774 0.78 POLB (0.62) PTPRCS100A4BCHEACHECES1
SCHEMBL22336272 0.78 PTPRC (0.59) PTPRCS100A4BCHEACHECES1
SCHEMBL9792088 0.78 PTPRC (0.61) PTPRCS100A4BCHEACHECES1
SCHEMBL2599382 0.78 PTPRC (1.00) PTPRCS100A4BCHEACHECES1
SCHEMBL1237207 0.78 PTPRC (0.91) PTPRCS100A4BCHEACHECES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108976133-A A kind of Triamine monomer of the structure containing phenanthrene ring and its preparation method and application 湖南工业大学 2018-12-11 CN disclosed