SCHEMBL28264657

SCHEMBL28264657

COc1ccc(CCC=O)c(OC)c1OC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.54
KDM4E B2RXH2 7/20 0.47
ALDH1A1 P00352 7/20 0.47
SMN1; SMN2 Q16637 3/20 0.45
TSHR P16473 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45
POLB P06746 2/20 0.43
CYP1A2 P05177 1/20 0.43
CHRM2 P08172 1/20 0.43
SLC6A4 P31645 1/20 0.43
OPRD1 P41143 1/20 0.43
OPRK1 P41145 1/20 0.43
APOBEC3A P31941 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42
KMT2A Q03164 4/20 0.41
MAPT P10636 2/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7333236 0.84 CA12 (0.54) KDM4EALDH1A1SMN1; SMN2TSHRPOLB
SCHEMBL7151009 0.81 AOC3 (0.49) AOC3KDM4EALDH1A1SMN1; SMN2TSHR
SCHEMBL7372077 0.78 KDM4E (0.60) AOC3KDM4EALDH1A1SMN1; SMN2TSHR
SCHEMBL11860893 0.78 AOC3 (0.43) AOC3KDM4EALDH1A1SMN1; SMN2TSHR
SCHEMBL27828875 0.77 CTSS (0.40) ALDH1A1TSHRPOLBCHRM2KMT2A
SCHEMBL27613891 0.77 AOC3 (0.61) AOC3KDM4EALDH1A1SMN1; SMN2TSHR
SCHEMBL4961141 0.77 AOC3 (0.61) AOC3KDM4EALDH1A1SMN1; SMN2TSHR
SCHEMBL30883 0.77 AOC3 (0.55) AOC3KDM4EALDH1A1SMN1; SMN2TSHR
SCHEMBL2689323 0.76 SLC2A1 (0.57) KDM4EALDH1A1SMN1; SMN2TSHRCYP1A2
SCHEMBL1253168 0.76 AOC3 (0.64) AOC3KDM4EALDH1A1SMN1; SMN2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109020792-A A method of synthesis β-O-4 lignin dimer model compound 中国科学院青岛生物能源与过程研究所 2018-12-18 CN claimed
CN-109020792-A A method of synthesis β-O-4 lignin dimer model compound 中国科学院青岛生物能源与过程研究所 2018-12-18 CN disclosed