SCHEMBL2826532

SCHEMBL2826532

CCc1[nH]c(C(=O)N[C@H]2CCN(c3nc(C(=O)NC)c(C(=O)O)s3)C[C@H]2OC)nc1Cl

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ABCC2 Q92887 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2850851 1.00 ABCC2 (0.58) ABCC2
SCHEMBL2850852 1.00 ABCC2 (0.58) ABCC2
SCHEMBL2847446 0.93 ABCC2 (0.52) ABCC2
SCHEMBL2847444 0.93 ABCC2 (0.52) ABCC2
SCHEMBL2849654 0.93 ABCC2 (0.57) ABCC2
SCHEMBL2849655 0.93 ABCC2 (0.57) ABCC2
SCHEMBL2854278 0.92 ABCC2 (0.52) ABCC2
SCHEMBL2854280 0.92 ABCC2 (0.52) ABCC2
SCHEMBL13173587 0.92 ABCC2 (0.57) ABCC2
SCHEMBL2851664 0.92 ABCC2 (0.57) ABCC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2226322-B1 IMIDAZOLE CARBONYL COMPOUND DAIICHI SANKYO CO LTD (JP) 2015-01-21 EP disclosed
EP-2226322-A1 IMIDAZOLE CARBONYL COMPOUND Daiichi Sankyo Company, Limited (JP) 2010-09-08 EP disclosed