Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.93 |
| ▸ | ATM | Q13315 | 1/20 | 0.93 |
| ▸ | F3 | P13726 | 2/20 | 0.70 |
| ▸ | GSK3B | P49841 | 2/20 | 0.66 |
| ▸ | BACE1 | P56817 | 1/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | BCHE | P06276 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | XDH | P47989 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Methoxycinnamic Acid SCHEMBL12473722 | 0.96 | THRB (1.00) | THRBATMF3GSK3BBACE1 | |
| 4-Methoxycinnamic Acid SCHEMBL58700 | 0.96 | THRB (1.00) | THRBATMF3GSK3BBACE1 | |
| 4-Methoxycinnamic Acid SCHEMBL58699 | 0.96 | THRB (1.00) | THRBATMF3GSK3BBACE1 | |
| 4-Methoxycinnamic Acid SCHEMBL711810 | 0.94 | THRB (0.96) | THRBATMF3GSK3BBACE1 | |
| 4-Methoxycinnamic Acid SCHEMBL10935651 | 0.94 | THRB (0.96) | THRBATMF3GSK3BBACE1 | |
| 4-Methoxycinnamic Acid SCHEMBL4654596 | 0.94 | THRB (0.96) | THRBATMF3GSK3BBACE1 | |
| 4-Methoxycinnamic Acid SCHEMBL8500105 | 0.94 | THRB (0.96) | THRBATMF3GSK3BBACE1 | |
| 4-Methoxycinnamic Acid SCHEMBL5330596 | 0.94 | THRB (0.96) | THRBATMF3GSK3BBACE1 | |
| 4-Methoxycinnamic Acid SCHEMBL5330605 | 0.94 | THRB (0.96) | THRBATMF3GSK3BBACE1 | |
| 4-Methoxycinnamic Acid SCHEMBL4652543 | 0.94 | THRB (0.96) | THRBATMF3GSK3BBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109161016-A | The preparation method of guanidine polymer heterogeneous catalyst and its catalyzing and synthesizing the application method in warfarin and its derivative | 河南工业大学 | 2019-01-08 | — | — | CN | disclosed |