Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 4/20 | 0.34 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | GPX4 | P36969 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.33 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20606593 | 0.84 | HCAR2 (0.38) | KDRCTNNB1WNT3AMAP4K4PIM1 | |
| SCHEMBL20606539 | 0.75 | POLB (0.48) | ARALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL15635227 | 0.73 | KCNMA1 (0.34) | KCNMA1MAP2K4CTNNB1WNT3AKMT2A | |
| SCHEMBL30398942 | 0.73 | SYK (0.40) | SYKKCNMA1KDRMEN1KMT2A | |
| SCHEMBL20936728 | 0.71 | AR (0.42) | ARALDH1A1LMNAKDM4E | |
| SCHEMBL31088779 | 0.71 | NOTUM (0.40) | KDRARMAP4K4PIM1GPX4 | |
| SCHEMBL30202675 | 0.70 | JAK2 (0.43) | SYKKCNMA1KDRKMT2AKDM4E | |
| SCHEMBL31465029 | 0.69 | KMT2A (0.38) | ARMAP2K4LMNAKMT2ASCN9A | |
| SCHEMBL16252832 | 0.68 | CTNNB1 (0.44) | KCNMA1ARCTNNB1WNT3AMEN1 | |
| SCHEMBL30448224 | 0.68 | SYK (0.43) | SYKPIM1PIM3IDO1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283920-B | 2, 4-disubstituted pyridine compound and application thereof | 贵州医科大学 | 2024-04-16 | — | — | CN | claimed |
| CN-116283920-A | 2, 4-disubstituted pyridine compound and application thereof | 贵州医科大学 | 2023-06-23 | — | — | CN | claimed |
| CN-109195965-A | The inhibitor that WDR5 protein-protein combines | 普罗佩纶治疗公司 | 2019-01-11 | — | — | CN | claimed |
| CN-116283920-B | 2, 4-disubstituted pyridine compound and application thereof | 贵州医科大学 | 2024-04-16 | — | — | CN | disclosed |
| CN-116283920-A | 2, 4-disubstituted pyridine compound and application thereof | 贵州医科大学 | 2023-06-23 | — | — | CN | disclosed |