Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10133319 | 0.89 | NPSR1 (0.64) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL16093698 | 0.80 | ALDH1A1 (0.58) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL29749450 | 0.78 | PTGER4 (0.72) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL4687926 | 0.78 | PTGER4 (0.72) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL28266267 | 0.77 | NPY5R (0.59) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL153959 | 0.76 | ALDH1A1 (0.62) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL30012682 | 0.76 | ALDH1A1 (0.62) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL30854944 | 0.76 | ALDH1A1 (0.62) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL17854676 | 0.76 | HPGD (0.63) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL29101964 | 0.75 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206360-A | Carbazole amide derivatives or its salt and its preparation method and application | 复旦大学 | 2019-01-15 | — | — | CN | disclosed |