Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PNKP | Q96T60 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28267282 | 1.00 | CSNK1E (0.37) | CSNK1EALDH1A1CYSLTR2CYSLTR1MEN1 | |
| SCHEMBL28269031 | 1.00 | CSNK1E (0.37) | CSNK1EALDH1A1CYSLTR2CYSLTR1MEN1 | |
| SCHEMBL28269030 | 1.00 | CSNK1E (0.37) | CSNK1EALDH1A1CYSLTR2CYSLTR1MEN1 | |
| SCHEMBL28269022 | 0.98 | CSNK1E (0.35) | CSNK1EALDH1A1CYSLTR2CYSLTR1MEN1 | |
| SCHEMBL28269020 | 0.98 | CSNK1E (0.35) | CSNK1EALDH1A1CYSLTR2CYSLTR1MEN1 | |
| SCHEMBL28267648 | 0.84 | — | — | |
| SCHEMBL28267646 | 0.84 | — | — | |
| SCHEMBL28267287 | 0.83 | MEN1 (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28267285 | 0.83 | MEN1 (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28269087 | 0.80 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111333-B | Chiral gem-disilyl alkane compound and synthesis method and application thereof | 浙江大学 | 2021-01-08 | — | — | CN | disclosed |
| CN-109111333-A | It is a kind of chiral together with two silicon substrate alkane compounds and its synthetic method and application | 浙江大学 | 2019-01-01 | — | — | CN | disclosed |