Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.86 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GGT1 | P19440 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiosalicylic Acid SCHEMBL28933918 | 0.93 | MAPT (0.91) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL3073817 | 0.93 | MAPT (0.91) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL50376 | 0.93 | MAPT (1.00) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL31208541 | 0.93 | MAPT (1.00) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL629705 | 0.93 | MAPT (1.00) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL28313023 | 0.93 | MAPT (1.00) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL28728288 | 0.91 | MAPT (0.86) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL28371699 | 0.91 | MAPT (0.95) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL8219754 | 0.91 | MAPT (0.95) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL28449890 | 0.91 | MAPT (0.95) | MAPTHDAC8ALDH1A1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563052-A | 5-amino-2, 3-dihydrothiazine-1, 4-dione crystals | 麦翠奥制药公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109071461-A | The method for preparing 5- amino -2,3- dihydro thiazine -1,4- diketone crystalline solid | 麦翠奥制药公司 | 2018-12-21 | — | — | CN | disclosed |