Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.54 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiosalicylic Acid SCHEMBL31208541 | 1.00 | MAPT (1.00) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL50376 | 1.00 | MAPT (1.00) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL28313023 | 1.00 | MAPT (1.00) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL28371699 | 0.97 | MAPT (0.95) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL10944700 | 0.97 | MAPT (0.95) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL28449890 | 0.97 | MAPT (0.95) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL27663081 | 0.97 | MAPT (0.95) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL8219754 | 0.97 | MAPT (0.95) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL27619473 | 0.97 | MAPT (0.95) | MAPTHDAC8ALDH1A1ALOX15KDM4E | |
| Thiosalicylic Acid SCHEMBL27484619 | 0.97 | MAPT (0.95) | MAPTHDAC8ALDH1A1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103728266-B | A kind of method prepared at the bottom of surface-reinforced infrared spectrum cobalt-based | SUZHOU UNIVERSITY (CN) | 2016-03-30 | — | — | CN | disclosed |
| CN-102507444-A | Auxiliary optical device of attenuation total reflection surface enhanced infrared spectrometer for DNA analysis | NANJING UNIVERSITY OF TECHNOLOGY | 2012-06-20 | — | — | CN | disclosed |
| EP-2420229-A1 | S-DIMETHYLARSINO-THIOSUCCINIC ACID S-DIMETHYLARSINO-2-THIOBENZOIC ACID S-(DIMETHYLARSINO) GLUTATHIONE AS TREATMENTS FOR CANCER | Board Of Regents, University Of Texas System (US) | 2012-02-22 | — | — | EP | disclosed |
| US-20110269697-A1 | ORGANOARSENIC COMPOUNDS AND METHODS FOR THE TREATMENT OF CANCER | SOLASIA PHARMA, K.K. (JP) | 2011-11-03 | — | — | US | disclosed |
| US-8045152-B2 | All optical nanoscale sensor | WILLIAM MARSH RICE UNIVERSITY (US) | 2011-10-25 | — | — | US | disclosed |
| EP-2321012-A1 | ORGANOARSENIC COMPOUNDS AND METHODS FOR THE TREATMENT OF CANCER | ZIOPHARM ONCOLOGY, INC. (US) | 2011-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269697-A1 | ORGANOARSENIC COMPOUNDS AND METHODS FOR THE TREATMENT OF CANCER | GSS, CTH, MALT1 | MAPT 4774/4885HDAC8 3902/4885ALDH1A1 1776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.