Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 8/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.48 |
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28268112 | 0.84 | NOTUM (0.66) | NOTUMKEAP1KCNH2RXRAGRIN1 | |
| SCHEMBL30538076 | 0.82 | NOTUM (0.63) | NOTUMKEAP1KCNH2RXRAGRIN1 | |
| SCHEMBL28266475 | 0.78 | RXRA (0.52) | NOTUMKEAP1KCNH2RXRAGRIN1 | |
| SCHEMBL16787394 | 0.78 | NOTUM (0.58) | NOTUMKEAP1KCNH2RXRAGRIN1 | |
| SCHEMBL20444416 | 0.78 | NOTUM (0.57) | NOTUMKEAP1KCNH2 | |
| SCHEMBL21792323 | 0.75 | NOTUM (0.70) | NOTUMKEAP1RXRAGRIN1GRIN2B | |
| SCHEMBL25045427 | 0.75 | NOTUM (0.68) | NOTUMKEAP1 | |
| SCHEMBL13735664 | 0.75 | NOTUM (0.58) | NOTUMKEAP1 | |
| SCHEMBL28267947 | 0.74 | RXRA (0.62) | KCNH2RXRAGRIN1GRIN2B | |
| SCHEMBL10447781 | 0.73 | NOTUM (0.78) | NOTUMKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071488-A | Substituted 1,2,3- triazole is as NR2B- selective NMDA regulator | 詹森药业有限公司 | 2018-12-21 | — | — | CN | disclosed |