Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | CBFB | Q13951 | 9/20 | 0.38 |
| ▸ | METAP2 | P50579 | 7/20 | 0.38 |
| ▸ | METAP1 | P53582 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460723 | 0.89 | NPC1 (0.41) | AURKANPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL28446738 | 0.88 | NPC1 (0.40) | AURKANPC1PKMRAB9ASMN1; SMN2 | |
| Iodide SCHEMBL11325081 | 0.88 | NPC1 (0.40) | AURKANPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL31229487 | 0.88 | NPC1 (0.40) | AURKANPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL28757530 | 0.88 | NPC1 (0.40) | AURKANPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL31678981 | 0.88 | NPC1 (0.40) | AURKANPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL6071532 | 0.88 | NPC1 (0.40) | AURKANPC1PKMRAB9ASMN1; SMN2 | |
| Iodide SCHEMBL11338884 | 0.87 | NPC1 (0.40) | NPC1PKMRAB9ASMN1; SMN2LMNA | |
| Bromide SCHEMBL11343585 | 0.87 | NPC1 (0.40) | AURKANPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL473160 | 0.83 | STAT3 (0.52) | NPC1RAB9ASMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109143655-A | A kind of intelligent dimming glass and its preparation method and application including metal organic frame film | 中国科学院福建物质结构研究所 | 2019-01-04 | — | — | CN | disclosed |