Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28264088 | 0.85 | HPGD (0.31) | KMT2AKDM4EMEN1MAPT | |
| SCHEMBL28268355 | 0.85 | HSD17B3 (0.34) | SLC6A2SLC6A4TRPM5NOTUM | |
| SCHEMBL28270399 | 0.81 | HIF1A (0.38) | HTT | |
| SCHEMBL28277626 | 0.80 | — | — | |
| SCHEMBL28255144 | 0.76 | — | — | |
| SCHEMBL28471512 | 0.69 | — | — | |
| SCHEMBL27963331 | 0.68 | HSD17B3 (0.32) | MAPT | |
| SCHEMBL28473087 | 0.67 | HTT (0.31) | HTT | |
| SCHEMBL28295382 | 0.67 | DRD2 (0.38) | SLC6A4NOTUMKMT2AMEN1 | |
| SCHEMBL28871821 | 0.67 | HSD17B3 (0.35) | KMT2AKDM4EMEN1MAPTNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232374-A | It is the method that one step of starting material constructs 2- tert-butyl -5- methylisoindoline -1,3- diketone using imines | 桂林理工大学 | 2019-01-18 | — | — | CN | claimed |
| CN-109232374-A | It is the method that one step of starting material constructs 2- tert-butyl -5- methylisoindoline -1,3- diketone using imines | 桂林理工大学 | 2019-01-18 | — | — | CN | disclosed |
| CN-109232374-A | It is the method that one step of starting material constructs 2- tert-butyl -5- methylisoindoline -1,3- diketone using imines | 桂林理工大学 | 2019-01-18 | — | — | CN | disclosed |
| CN-109232374-A | It is the method that one step of starting material constructs 2- tert-butyl -5- methylisoindoline -1,3- diketone using imines | 桂林理工大学 | 2019-01-18 | — | — | CN | disclosed |