Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27776290 | 0.91 | STS (0.50) | STSSMN1; SMN2NPC1HTTRAB9A | |
| SCHEMBL8083202 | 0.90 | STS (0.56) | STSSMN1; SMN2NPC1HTTRAB9A | |
| SCHEMBL15939439 | 0.86 | STS (0.49) | STSSMN1; SMN2NPC1HTTRAB9A | |
| SCHEMBL1976081 | 0.84 | STS (0.62) | STSSMN1; SMN2NPC1HTTRAB9A | |
| SCHEMBL23518946 | 0.84 | STS (0.56) | STSSMN1; SMN2NPC1HTTRAB9A | |
| SCHEMBL28266819 | 0.82 | TAS1R3 (0.54) | HSD11B1MAPTEPHX2EPHX1MGLL | |
| SCHEMBL27519964 | 0.81 | STS (0.55) | STSSMN1; SMN2NPC1HTTRAB9A | |
| SCHEMBL28097193 | 0.81 | EPHX2 (0.44) | STSSMN1; SMN2NPC1HTTRAB9A | |
| SCHEMBL9541270 | 0.80 | STS (0.59) | STSSMN1; SMN2NPC1HTTRAB9A | |
| SCHEMBL29159624 | 0.79 | TAS1R3 (0.57) | STSSMN1; SMN2NPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109219602-A | Modulators of cystic fibrosis transmembrane conductance regulator proteins | 艾伯维公司 | 2019-01-15 | — | — | CN | disclosed |