Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | ITGAL | P20701 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyne SCHEMBL28266950 | 0.81 | AHR (0.52) | AHRMEN1POLBMAPK1KMT2A | |
| SCHEMBL11994 | 0.81 | AHR (0.56) | AHRMEN1POLBMAPK1KMT2A | |
| SCHEMBL29556250 | 0.81 | AHR (0.56) | AHRMEN1POLBMAPK1KMT2A | |
| SCHEMBL4656311 | 0.79 | AHR (0.50) | AHRMEN1POLBMAPK1KMT2A | |
| Pyridine SCHEMBL28518714 | 0.76 | MEN1 (0.43) | AHRMEN1POLBMAPK1KMT2A | |
| Benzoic Acid SCHEMBL11438463 | 0.75 | ALDH1A1 (0.63) | MEN1KMT2AESR1CYP19A1TYR | |
| SCHEMBL9262684 | 0.75 | GRM5 (0.57) | AHRMEN1POLBMAPK1KMT2A | |
| SCHEMBL17291794 | 0.74 | MEN1 (0.48) | AHRMEN1POLBMAPK1KMT2A | |
| Indole SCHEMBL28785692 | 0.71 | AHR (0.63) | AHRMEN1POLBMAPK1KMT2A | |
| SCHEMBL8186590 | 0.70 | CYP2A6 (0.44) | AHRMEN1POLBMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997197-A | A kind of cyano carbazole analog derivative and its synthetic method | 华东师范大学 | 2018-12-14 | — | — | CN | disclosed |